Medical condition

This regulation prohibits you from operating a drone or participating in drone operations if you know—or should reasonably know—that you have a physical or mental condition that would interfere with safe operation.

This applies to anyone involved in the flight operation:

• Remote pilots in command
• Visual observers
• Anyone manipulating the flight controls
• Direct participants in the operation

The key is self-assessment: you're responsible for determining whether any condition (fatigue, illness, medication effects, injury, emotional distress, etc.) impairs your ability to operate safely. Unlike manned aircraft pilots, Part 107 remote pilots don't need an FAA medical certificate, but you must still ensure you're fit to fly. If you're impaired in any way that could compromise safety—even temporarily—you cannot legally operate or participate in the drone operation until the condition resolves.

*This is a plain-English summary for study only. The official 14 CFR text on this page is controlling — always read the current regulation and consult a CFI.*